What has SMC said?
The Scottish Medicines Consortium (SMC) has accepted sodium thiosulfate to reduce the risk of hearing loss caused by a type of chemotherapy medicine called cisplatin. It is for use in children who are 1 month to 18 years old and who are receiving cisplatin-based chemotherapy to treat a solid tumour that has not spread.
This document summarises the SMC decision and what it means for patients.
You can find more detailed information about the SMC assessment of sodium thiosulfate by looking at the SMC Detailed Advice Document (SMC2730).
What does SMC’s decision mean for patients?
Sodium thiosulfate for use as described above is available for prescribing on the NHS in Scotland. Your healthcare professional can discuss with you if it is the right treatment for you or your child.
You can find more information about making decisions about your or your child’s treatment in this booklet called: Medicines in Scotland: What’s the right treatment for me? - Information for patients and the public
More about SMC’s decision
SMC’s decision takes into account a confidential discount offered by the pharmaceutical company. SMC was also able to be more flexible* in its decision-making because the medicine is for a rare condition.
How does SMC make its decision?
SMC carefully considers every new medicine to make sure it benefits patients and is likely to be a good use of NHS resources.
To do this SMC studies the following:
• Evidence from the company about how well the medicine works compared with current treatments available in Scotland, in relation to how much they will cost to buy and use to treat patients.
• Information from patient groups about the potential impact of the medicine on patients and carers.
•Advice from healthcare professionals about any benefits of the new medicine compared to current treatment, along with how the new medicine is likely to be used.
When SMC assesses a medicine it takes account of the needs of all patients in NHSScotland, not only those who may be treated with the medicine.
You can find out more about how SMC decides here: https://www.scottishmedicines.org.uk/how-we-decide/
More information and support
The organisations below can provide more information and support for people affected by hearing loss and their families. SMC is not responsible for the content of any information provided by external organisations.
Royal National Institute for Deaf People
https://rnid.org.uk 0808 808 0123
National Deaf Children’s Society
https://www.ndcs.org.uk 0808 800 8880
You can find out more about sodium thiosulfate (brand name: Pedmarqsi®) in the Patient Information Leaflet (PIL) by searching for the medicine name on the Medicines and Healthcare products Regulatory Agency (MHRA) website.
https://products.mhra.gov.uk/